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ALTALATGPT Test

ALTALATGPT Test

Alanine aminotransferase (glutamate pyruvate transaminase) belongs to the group of transaminases, which catalyze the conversion of amino acids to the corresponding α-keto acids via the transfer of amino groups; they also catalyze the reverse process. Although higher activities exist in the liver, minor activity can also be detected in the kidneys, heart, skeletal muscle, pancreas, spleen, and lungs. Elevated serum ALT is found in hepatitis, cirrhosis, obstructive jaundice, carcinoma of the liver, and chronic alcohol abuse.

ALT is only slightly elevated in patients who have an uncomplicated myocardial infarction.

Although both serum aspartate aminotransferaseAST) and ALT become elevated whenever disease processes affect liver cell integrity, ALT is the more liver-specific enzyme. Moreover, elevations of ALT persist longer than elevations of AST activity.

SPECIMEN

Serum, EDTA or heparinized plasma. Avoid hemolysis.

Expected values:

                                                    Male                Female

                             25ºC             Up to 22 U/l         Up to 17 U/l

                            30ºC              Up to 29 U/l         Up to 22 U/l

                            37ºC              Up to 41 U/l        Up to 31 U/l.

ALTALATGPT Test

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