Activated Partial Thromboplastin Time (aPTT)

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Activated Partial Thromboplastin Time (aPTT)

Activated Partial Thromboplastin Time (aPTT)

Test the efficiency of the intrinsic pathway, i.e. factors: XII, HMWK, prekallikrein, XI, X, IX, VIII, V, II, and fibrinogen.

this test is used to monitor patients on therapeutic heparin anticoagulation.

Specimen

Non-lipemic, non-icteric platelet-poor plasma (PPP) derived from whole blood (WB) collected in a plastic blood tube containing 1 part buffered 3.2% sodium citrate for each 9 parts WB.

Uses of APTT:

• To detect intrinsic factor deficiency.
• To monitor Heparin therapy.
• To detect circulating anticoagulants/inhibitors against intrinsic factors.
• Preoperative screening.
• Screening for Lupus inhibitors.

Reporting Results:

Results are reported as APTT ratio:-

Patient APTT time

APTT Ratio  =     ————————————-

Normal Control APTT time

Normal range :

Normal time of APTT vary according to the manufacturer of the partial thromboplastin.

Generally it is between 20-35 seconds.

Activated Partial Thromboplastin Time (aPTT)

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