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Aldosterone and Renin Test
Aldosterone and Renin Test
Aldosterone is a hormone that plays an important role in maintaining normal sodium and potassium concentrations in blood and in controlling blood volume and blood pressure. Renin is an enzyme that controls aldosterone production.
Aldosterone is produced by the adrenal glands located at the top of each kidney, in their outer portion (called the adrenal cortex).
Aldosterone stimulates the retention of sodium (salt) and the excretion of potassium by the kidneys.
Renin is produced by the kidneys and controls the activation of the hormone angiotensin, which stimulates the adrenal glands to produce aldosterone.
The kidneys release renin when there is a drop in blood pressure or a decrease in sodium chloride concentration in the tubules in the kidney. and it stimulates aldosterone production. Overall, this raises blood pressure and keeps sodium and potassium at normal levels.
These tests are most useful in testing for primary aldosteronism, also known as Conn syndrome, which causes high blood pressure. If the test is positive, aldosterone production may be further evaluated with stimulation and suppression testing.
Both aldosterone and renin levels are highest in the morning and vary throughout the day. They are affected by the body’s position, by stress, and by a variety of prescribed medications.
A blood aldosterone test and a renin test are usually ordered together when someone has high blood pressure, especially if the person also has low potassium. Even if potassium is normal, testing may be done if typical medications do not control the high blood pressure or if hypertension develops at an early age. Primary aldosteronism is a potentially curable form of hypertension, so it is important to detect and treat it properly. Aldosterone levels are occasionally ordered, along with other tests, when a doctor suspects that someone has adrenal insufficiency.
Sample :
Whole blood and Some doctors prefer 24-hour urine collection for aldosterone since blood aldosterone levels vary throughout the day and are affected by position.
Aldosterone and Renin Test
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