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Cancer Antigen-Breast (CA15.3) Test

Cancer Antigen-Breast (CA15.3) Test

Cancer antigen 15-3 (CA 15-3) is a protein that is produced by normal breast cells. In many people with cancerous breast tumors.

CA 15-3 is elevated in only about 10% of women with early localized breast cancer but is elevated in about 80% of those with metastatic breast cancer.

CA 15-3 may also be elevated in healthy people and in individuals with other cancers (e.g., colon, lung, pancreas, ovary, or prostate malignancies) or certain conditions (e.g., cirrhosis, hepatitis, and benign breast disease).

CA 15-3 is not sensitive or specific enough to be considered useful as a tool for cancer screening.

CA 15-3 is sometimes ordered to give a doctor a general sense of how much cancer may be present (the tumor burden)

CA 15-3 may be ordered along with other tests, such as estrogen and progesterone receptors, and gene expression tests for breast cancer, when advanced breast cancer is first diagnosed to help determine cancer characteristics and treatment options. If CA 15-3 is initially elevated, then it may be ordered periodically to monitor the effectiveness of treatment and to help watch for recurrence.

CA 15-3 is usually not ordered when breast cancer is detected early, before it has metastasized, because levels will not be elevated in the majority of early cancers.

Sample :

Whole blood.

Cancer Antigen-Breast (CA15.3) Test

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