Hello

Entameba Histolytica

Entameba Histolytica

– Many species of the genus Entameba infect human but E.histolytica is the only species cause disease.

-Disease : amebic dysentery and liver abscess.

– Important properties : life cycle has 2 stages

( motile stage (trophozoites) and the non-motile form (cysts).

Trophozoite stage:

– Trophozoites present in intestinal and extraintestinal lessions (i.e. liver, blood & brain ) & in diarrheal stool.

– 60 µ, asymmetric, purposeful directional motility, single spherical nucleus, single central karyosome, delicate and evenly distributed chromatin.

-Able to lyse tissues.

-Lives in flask-shaped

– ulcers in mucosa results from lyses by ameba.

– Divide by binary fission.

Cyst stage :

– Spherical, 10-20 µ mature cyst has 4 nuclei with compact centrally located karyosome; chromatin is delicate. Some cysts may have chromatoid bars.

– Predominates in non-diarrheal stool, highly resistant but killed by boiling not killed by chlorination, removed by filtration.

Upon exocystation in intestine nuclei divides into 8 trophozoites.-

In extra intestinal amebiasis no cyst form.-

Lab results may reveal an increase in ESR, low degree of PMNs.

Entameba Histolytica Life Cycle:

Entameba Histolytica

Pleased traffic

(If you like this topic , publish it plz)